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Vigorous shaking can damage the delicate peptide chains through mechanical stress, a process called shearing

DOI:10.1016/S0736-0266(03)00110-4 D.Pevec, T.Novinscak, L.Brcic, K.Sipos, I.Jukic, M.Staresinic, S.Mise, Impact of pentadecapeptide BPC 157 on muscle healing impaired by systemic corticosteroid application

To investigate this, we treated brain slices with CPZ alone, or in the presence of the cytokines TNFa and IFNg, or with the pro-inflammatory compound lipopolysaccharide (LPS), which we have previously demonstrated to induce demyelination in longitudinal organotypic spinal cord slice cultures (Hawker et al., 2024)

Do not place it near a heat source