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Age, sex, nutritional status, adiposity, dietary preferences, habits such as smoking, use of concurrent medications, physiologic states such as pregnancy, pathologic states such as liver disease, and others can affect one or more of the 3 processes listed above, thereby influencing the half-life of psychotropic and other drugs

While chronic fatigue can persist over time and may be linked to underlying health conditions, sudden crashing fatigue is often episodic and can be triggered by various factors

Vasc Health Risk Manag 8:415427 Ryan JR, Jain A (1972) The effect of colestipol or cholestyramine on serum cholesterol and triglycerides in a long-term controlled study

Age does not appear to affect the absorption of vitamin B12, ensuring consistent retention across different age groups