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Treatment with XH significantly reduced the phosphorylation of TOPK as well as its downstream signaling molecules Akt and histone H3 in A549 and HCC827 cells and also suppressed its kinase activity
Heat shock protein 90 as therapeutic target for CVDs and heart aging
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However, phosphorylation of JNK was detectable at 6 h while that of ERK started appearing at 12 h when HCH and BSO were combined (Fig
