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Description
Glutathionylation of the active site cysteine, a prerequisite for enzymatic activity, occurs only under highly oxidizing conditions established by the GSH/glutathione disulfide (GSSG) redox couple, while class I GRXs are readily glutathionylated even at very negative GSH/GSSG redox potentials

Immunocal Preserves Cellular GSH and Prevents Apoptosis in CGNs Exposed to the Bcl-2 Inhibitor, HA14-1 Initially, primary CGNs were incubated with 3.3% ( w / v ) Immunocal for 24 h to assess any potential toxicity that this supplement might induce

Leyden JJ, Stephens TJ, Finkey MB, Appa Y, Barkovic S

10.1681/ASN.2004070568 86 KomersR.LindsleyJ
