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The PTEN-induced kinase 1 (PINK1)/Parkin pathway serves a pivotal role in the context of mitochondrial dysfunction and its association with PD

Clinically, DNA methylation markers hold promise for predicting therapeutic responses, though their utility is hindered by insufficient validation and off-target effects

Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin
