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L-Carnitine: Plays a critical role in fatty acid metabolism and mitochondrial health

Two of the largest RCTs assessed the risk of HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome (N=12,901 women) and found an increased risk of HELLP with calcium supplementation compared with placebo (RR 2.67, 95% CI: 1.05-6.82)

This method boasts high precision, small sample size, and short analytical time, allowing for the simultaneous quantification of carnitine and acylcarnitines in a single sample and applicable to other acylcarnitines as well

Given these functions, carnitine is concentrated in tissues that utilize fatty acids as fuel, like skeletal and cardiac muscles