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Disruption of the Hedgehog signaling pathway can drive macrophages to prioritize glycolysis over fatty acid oxidation, effectively shifting them from an M2 phenotype to an M1-like phenotype

When the antioxidant glutathione is administered intravenously, this causes an immediate boost in energy since the antioxidant is known to enhance mitochondrial energy production in cells

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Moreover, coumarins except for the cancer treatment support have the potential to neutralize the side effects associated with radiotherapy