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These events were Ca 2+ -dependent and could be prevented by Ca 2+ chelation

While antioxidant supplementation has shown promise, there is still a need to determine the optimal types, doses, and combinations of antioxidants that are most effective for reducing oxidative stress and improving fertility outcomes

This is consistent with our previous data, which showed that lipid peroxidation was significantly increased while reduced glutathione (GSH) and glutathione-dependent antioxidant enzymes activity markedly decreased in blood of patients with PD as well as in rat brain under modeling of PD 7

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