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Two forms of human COMT have been identified, a cytoplasmic soluble form (SCOMT) and a membranebound form (MBCOMT) located in the cytosolic side of the rough endoplasmic reticulum The SCOMT is predominantly expressed in the human liver, intestine and kidney (Taskinen et al., 2003), whereas the membranebound form is more highly expressed in all regions of the human central nervous system (Tunbridge et al., 2006)

Reduction in Inflammation One study examined how BPC-157 affected tissues irritated by capsaicin (the active component in chili peppers) in rat noses

5 mm ammonium formate)