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Cellular GSH is a major defense against the redox cycling-derived oxidative stress and therefore a detailed model of glutathione-quinone interplay is of great interest to cancer treatment and analysis of side effects [169]

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In humans, cyanocobalamin must undergo intracellular enzymatic conversion to the active coenzyme formsmethylcobalamin and adenosylcobalaminwhich, depending on the pH environment, can interconvert with hydroxocobalamin (Obeid et al., 2015)