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Therefore, chronic stress-induced dysregulation of the HPA axis, potentially mediated by imbalances in gut microbiota, might be a crucial link between dysbiosis and the progression of AD (Figure 1)

Haupt S, Caramia F, Herschtal A, Soussi T, Lozano G, Chen H, et al
Yan J, Peng Y, Huang S, Fei W, Chen Y, Zheng C, et al

doi: 10.3389/fimmu.2022.970906