glp/gip/glucagon & cagrilintide Efficacy and safety of incretin co-agonists: Transformative advances in cardiometabolic healthcare nejm Semaglutide, a glucagon-like peptide-1
Description
Although LA is targeted specifically to the GI tract due to its nonabsorbed nature, understanding how long various formulations of the drug take to reach specific regions within the small intestine and in therapeutically effective concentrations are crucial for its use in other clinical conditions
This makes validation, replication, and troubleshooting significantly more difficult
1 2 3 Lancet
Dietary modifications, dose reduction, or slower titration may improve tolerability whilst maintaining therapeutic benefit
