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10.1053/j.gastro.2010.08.023 120 ZhangY

Tirzepatide is a dual-agonist , meaning it works by targeting two hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Retatrutide is a triple-agonist , meaning it targets three hormones: GLP-1: helps regulate appetite, blood sugar, and digestion GIP: supports insulin response and reduces nausea Glucagon: affects energy use and fat metabolism Early studies show that retatrutide may be more successful than tirzepatide at managing diabetic kidney disease, as well as for weight control, while tirzepatide may be better at managing blood glucose

doi: 10.1016/j.genm.2010.11.010 174 McKayK

O GHK-Cu um complexo peptdico ligado ao on cobre (Cu), amplamente estudado por sua interao com protenas da matriz extracelular e por sua participao em vias de sinalizao celular