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E.Lannes-VieiraJ.et al

IB kinase promotes Nrf2 ubiquitination and degradation by phosphorylating cylindromatosis, aggravating oxidative stress injury in obesity-related nephropathy

mTORC1 is a central driver of metabolic reprogramming, activated in cancer cells downstream of PI3K/AKT, and orchestrating both glucose and lipid metabolism

Conclusion We conclude that proactive optimization of NEAA status through targeted supplementation or metabolic activation represents a low-risk, biologically rational adjunct to enhance postoperative outcomes in geriatric maxillofacial patients
