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doi: 10.1038/s41467019-092779 237 MiessHDankworthBGouwAMRosenfeldtMSchmitzWJiangMet al

doi: 10.1007/s40263-020-00779-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 64.Sparshatt A, Taylor D, Patel MX, Kapur S

Thymogen Alpha-1 targets immune function

The sandwich method is a simple way to reduce irritation: Apply a thin layer of moisturizer on clean, dry skin Apply a pea-sized amount of tretinoin (avoid corners of nose, mouth, and eyelids) Finish with another thin layer of moisturizer Two important details: Start slow: 23 nights/week, then increase only if your skin is calm
