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If immunoglobulin E (IgE) is involved in the reaction then the term IgE mediated food allergy should be used and the term non-IgE mediated food allergic reactions used for immune mediated reactions that are not mediated by IgE

Clinical studies have demonstrated that an 8-week IF intervention can affect immune and inflammatory pathways, leading to a reduction in tumor necrosis factor-alpha (TNF-) and other cytokines in overweight or obese adults [2]

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