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Thiostrepton (TS) induces apoptosis in patient-derived mesothelioma explants Interrogation of the Cancer Dependency Map (DepMap) 21 showed that the small molecule PRX3 inhibitor TS efficiently reduced the viability of a panel of 578 human tumor cell lines (Supplementary Fig
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Certain groups are at higher risk, including older adults, vegans, individuals with pernicious anaemia, those with malabsorption conditions such as Crohn's disease or coeliac disease, and people taking certain medications (metformin, proton pump inhibitors)

This review analyzes the antioxidant, anti-inflammatory, and neuroprotective effects of ALA and discusses its applications as an ameliorative tool for chronic diseases and those associated with oxidative stress
