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Description
PGD 2 production in DMD is involved in the expansion of muscular necrosis caused by muscular inflammation based on the observation that the administration of HPGDS inhibitors, including HQL79, TAS204, and TAS205, ameliorates muscular atrophy by decreasing urinary tetranor-PGDM concentrations in animal models 10,19,20,21 and in patients with DMD 22,23
(1976) Toxicity of four pesticides to water fleas and fathead minnows, Duluth, Minnesota, US Environmental Protection Agency, Environmental Research Laboratory, Office of Research and Development, (Ecological Research Series EPA-600/3-76-099)

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Sokolova et al., 2024)
