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The global geomean titer (GGMT) against the mismatched viruses was higher for the E2E1-NP immunized rabbits, but differences were not statistically significant (median GGMT of 34 for E2E1-NP versus 21 and 21 for E2 and E2E1-I53-50A, p = 0.08 and p = 0.18, respectively)

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Microglial NF-B activation under GSH-depleted conditions creates a pro-inflammatory loop where increased ROS promotes NF-B activation, which upregulates inflammatory cytokines and further stimulates oxidative stress (Liu et al., 2017
Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597