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CAFs can recruit myeloid-derived immunosuppressive cells (MDSCs) and regulatory T cells (Tregs) by up-regulating the expression of chemokines CCL22 and CCL28, and further enhancing immunosuppressive TME (71)

This suggests that rG4 may be a general property of the strong RNA inhibitors capable of mitigating FUS LLPS

Cryogenic electron microscopy The specimens for cryogenic electron microscopy (Cryo-EM) have been prepared onto 300 mesh Ultrafoil Au R1.2/1.3 grids (Quantifoil Micro Tools GmbH, Germany)

Consequently, we used fluorescently-labeled concanavalin A to visualize slime secretion in living cells to determine whether slime trails emerged from the cross walls, where nozzles are located