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Previous studies have shown that a small molecule called Ras Lethal 3 ((1S,3R)-RSL3,(RSL3)) can pharmacologically inhibit GPX4 in skin and soft tissue cancer models in vitro and leads to induction of ferroptosis 10,11

Mount Sinai Health System

10.3389/fpsyt.2023.1225794 35 Glover-WrightC.CoupeK.CampbellA
