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Ann Transl Med 6:467 Higgins T, Chaykin S, Hammond KB, Humbert JR (1972) Trimethylamine N-oxide synthesis: a human variant

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eLife 8 , e44527 (2019)

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Dysbiosis impairs the intestinal barrier, increasing its permeability and allowing bacteria and lipopolysaccharides (LPS) from the gut to translocate into the systemic circulation, leading to systemic inflammation (148)

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Weinstein S, Toker IA, Emmanuel R, Ramishetti S, Hazan-Halevy I, Rosenblum D, Goldsmith M, Abraham A, Benjamini O, Bairey O, Raanani P, Nagler A, Lieberman J, Peer D

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