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Equids, especially horses, are very susceptible to the infection
Interestingly, NOX-derived ROS are linked to activating mutations in FLT3 and Ras: FLT3-ITD mutation in AML causes Akt activation and subsequent stabilization of p22 phox , a regulatory subunit for NOX1-4 [93, 95]
Katayama R, Nagata S, Iida H, Yamagishi N, Yamashita T, Furuhama K (2011) Possible role of cysteine-S-conjugate -lyase in species differences in cisplatin nephrotoxicity
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