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Up-regulation of K+ channels in diabetic rat ventricular myocytes by insulin and glutathione

This process involves the accumulation of glycosaminoglycans within the valve layer, leading to structural weakening and leaflet redundancy

Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K (2007) Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinsons disease

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