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Some conditions that can cause this vitamin B12 deficiency include: Atrophic gastritis, an inflammation of the stomach Surgical removal of part of the stomach or intestines Conditions that affect your intestine's ability to absorb nutrients, such as Celiac disease Pancreatic insufficiency Alcoholism Acquired immune deficiency syndrome (AIDS) Some people who don't have enough of a protein called the "intrinsic factor" also have a vitamin B12 deficiency

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GSH degradation is catalized by -glutamyltranspeptidase (GGT), an enzyme that catalyzes the cleavage of the peptide bond between cysteine and the -carboxyl group of glutamate, and the transfer of the -glutamyl moiety to water (hydrolysis), an amino acid, or a short peptide (transpeptidation) (Mitri and Castellano, 2023)

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