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They include enzymatic degradation by proteases or peptidases, low permeability across the mucosal epithelium, and rapid clearance due to salivary dynamics
RK12V-SP cells showed self-renewal capacity, the potential to develop into stromal cells, reduced expression levels of differentiation markers, long-term proliferating capacity in cultures, and enhanced tumorigenicity, indicating that RK12V-SP cells have cancer stem-like cell features
Molecular functions are best understood for the yeast GID E3, which regulates nutrient-dependent control of carbon metabolism 10,11,12,13,14,15,16
