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Metabolomics Profiling of White Button, Crimini, Portabella, Lion's Mane, Maitake, Oyster, and Shiitake Mushrooms Using Untargeted Metabolomics and Targeted Amino Acid Analysis

Notably, the 'metabolism of xenobiotics by cytochrome P450' pathway showed pronounced enrichment in both transcriptional and proteomic profiles, suggesting that the activation of drug-metabolizing genes and proteins may contribute to toxicological responses by indirectly modulating metabolite accumulation