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The defining characteristics of cancer cells lie not only in their uncontrolled proliferation but also in their unique energy metabolism patterns [120]

GodosJFerriRLanzaGCaraciFVistorteAORYelamos TorresVet al

These neurotrophic factors have broad anti-apoptotic effects (87), with BDNF modulating hippocampal long-term potentiation (LTP) and synaptic plasticity to enhance learning and memory (103)

These effects are presumably due, at least in part, to complex I inhibition of the ETC, which significantly perturbs mitochondrial function [82,83]
