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Applying a topical numbing cream (5% lidocaine) 1520 minutes before injection numbs the skin surface and reduces initial needle sensation

By contrast, SIRT1 downregulation as the results of cardiovascular risk factors induces an open chromatin eventually leading to p66 Shc expression, mitochondrial oxidative stress and endothelial dysfunction (138)

10.5530/pj.2022.14.15 7 AkhtarN

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