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Possible risks include temporary or persistent sensitivity, gum irritation, bite discomfort, crown fracture, recurrent decay at the margins, and in some cases the need for root canal treatment

However, its use for bodybuilding or as part of Post Cycle Therapy (PCT) without a doctors prescription is often restricted or illegal

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thus, there is an urgent need for an effective intervention to reset the circadian clock and prevent metabolic syndrome and metabolic syndrome-induced cancers