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Lifespan control by redox-dependent recruitment of chaperones to misfolded proteins

Cells were lysed with RIPA buffer, and the lysates were subjected to SDS-PAGE and visualized by Western blotting using antibodies against PGRMC1, EGFR, phospho-Y1068 EGFR (Cell signaling: #2234S), AKT (Cell signaling: #9272S), phospho-S473AKT (Cell signaling: #4060S), ERK (Cell signaling: #4695S) and phospho-T185 Y187 ERK (Invitrogen: 44680 G)

The scan speed was 25 m/s and 0.8 l/min helium gas flow

Figure 8 Discussion Mounting evidence has shown that m6A modification is critical to mitigating the progression of various cancers, including endometrial cancer ( In the human mRNA level, m6A is considered to be the most enriched internal chemical modification