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Indeed, we found no significant increase in cellular ROS after the addition of BHB (Extended Data Fig

Unaugmented Gpx/GR Ratio In previous simulations, the standard model involved a higher concentration of Gpx (2 M) than that of GR (0.05 M), following from our proposed order of genes in the plasmid

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Free Radic Biol Med 65:789799 Ibez L, Ferrndiz ML, Brines R, Guede D, Prez-Crceles MD, Alcaraz MJ (2014) Effects of Nrf2 deficiency on bone microarchitecture in an experimental model of osteoporosis