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Description
Insufficient sleep can cause increased cytokine secretion provoking an inflammatory response in various tissues including the brain which is associated with cognitive impairment [2]
It is unknown if this is the case in humans

Low-Dose Naltrexone (0.5 to 4.5mg) briefly blocks receptors for a few hours, triggering your body to produce more endorphins

ODriscoll, C.M., Griffin, B.T., Biopharmaceutical challenges associated with drugs with low aqueous solubility The potential impact of lipid-based formulations, Advanced Drug Delivery Reviews, 60
