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Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of tlr4

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Dudvarski Stankovic N, et al

The downregulation of KLF2 expression is significantly correlated with the TNM staging of ccRCC, and ccRCC patients with low expression of KLF2 have significantly shorter overall survival and metastasis-free survival periods

Clinicians will adjust the dose of ICS based on the patients symptom severity, history of acute exacerbations, and other co-morbidities to ensure that treatment is both effective and safe (182)
