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Sorbo 1987), transamination is not thought to be an important pathway for whole-body Cys catabolism or desulfuration under normal physiological conditions (Stipanuk and Beck 1982

For example, when cardiomyocytes were incubated with the taurine transporter antagonist (guanidinoethane sulfonate-GES) or taurine transporter inhibitor (-alanine), mitochondrial oxidative stress increased and was accompanied by an accumulation of superoxide anions (O2), glutathione oxidation (GSSG), and inactivation of anti-oxidant enzymes such as aconitase (46,50)

Mesenchymal stromal cells: heterogeneity and therapeutical applications

Figure 3 Apart from the genetic susceptibility to ferroptosis, microglial sensitivity to ferroptosis also depends on its state and was affected by iNOS/NO