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Description
The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)
Oral administration, despite its lower bioavailability due to first-pass metabolism, is under investigation for its potential benefits in chronic pain and depression
46 JeonS
doi: 10.1097/HEP.0000000000000696 20
