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According to IQVIA prescription data, GLP-1 receptor agonist prescriptions increased dramatically between 2020 and 2024, and that growth has continued into 2026 as new medication formats enter the market

This suggests that systemic endothelial dysfunction may be a primary factor in the development of systemic hypertension and its pathological consequences, such as increased left ventricular wall stress, hypertrophy, diastolic dysfunction, and HFpEF [22]

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How do GLP-1 medications work
