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accordingly, future studies that include the effects of glucagon receptor signaling on aging in female mice will be important to understanding potential sex differences in the role of glucagon signaling in aging and the response to caloric restriction

Following reporting guidelines such as STROBE (STrengthening the Reporting of OBservational studies in Epidemiology) greatly improves the assessment of strengths and weaknesses of studies reported in literature, improves the quality of observational studies, and aids multi-centre international studies to adhere to local regulations and best practices (von Elm et al

272,275 see Figure 23

Schousboe A, Bak LK, Waagepetersen HS (2013) Astrocytic control of biosynthesis and turnover of the neurotransmitters glutamate and GABA