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Recently, PET ligands binding to synaptic vesicle 2a (SV2a), such as 11C-UCB-J, have been developed, providing a in vivo marker of synaptic density, thought to be a key pathomechanism in PD and PD progression to dementia 251

Other cannabinoids include cannabidivarin (CBDV), delta-9-tetrahydrocannabivarin (THCV), cannabichromene (CBC), delta-8-THC, and cannabinol (CBN) (Figure 1)
