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All data were analyzed using the SAS software package, release 9.4 (SAS Institute), or using R software (R version 4.1.2)

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AOD9604 may synergize with this state Protocol: inject on waking, wait 3060 minutes before eating Benefits: may maximize fat-burning effects Most common protocol in clinical research Pre-exercise dosing: Rationale: may enhance fat oxidation during exercise Protocol: inject 3060 minutes before training Benefits: potential synergy with exercise-induced lipolysis Suitable for research combining the peptide with exercise interventions Pre-meal dosing: Rationale: may help prevent fat storage from meals Protocol: inject 30 minutes before meals Benefits: theoretical advantage for preventing lipogenesis Less commonly used

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