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The mechanistic explanation is signal convergence: cAMP-PKA signaling from GHRH receptor activation and calcium-PLC-PKC signaling from ghrelin receptor activation independently sensitize the GH secretory machinery and prime GH vesicle release through complementary pathways

Jiang L, Wang J, Wang K, Wang H, Wu Q, Yang C, et al

Gumz ML, Zou H, Kreinest PA, Childs AC, Belmonte LS, LeGrand SN, et al

*Correspondence: Yulan Li, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers