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Special emphasis should also be placed on evaluating their potential in combination with CFTR modulators and antimicrobial therapies, which may open new therapeutic avenues for effective disease management

Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5xFAD mouse model of Alzheimers disease. Molecular neurodegeneration vol

These factors may interact with genetic predispositions and contribute to the development or exacerbation of dystonic symptoms

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