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Treatment of cultures with B12 increased methylation levels of CpGs at chr17: 36,090,097 in MOD subjects and at chr17: 36,090,097, 36,090,102 and 36,090,246 in SEV subjects compared to their respective cultures at endpoint A
We also found human and mouse -cells and -cells express the L-type amino acid transporter (LAT) isoforms required for cellular uptake of catecholamine precursors (e.g., L-DOPA)
The signs you may need B12 supplementation include persistent fatigue, neurological changes, and blood-related abnormalities
