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Some medications can reduce the ability to absorb vitamin b12, such as proton pump inhibitors, and PPIs

This not only enhances patient compliance but also reduces the likelihood of side effects associated with more complex treatment regimens

The dark_ref_SACLA model is represented as sticks with the four-helix bundle residues W131 and H132 coloured pale yellow and the Rossmann fold domain residue H177 and the AdoCbl in light blue

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