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Description
Various cell types, such as intervertebral disc-derived cells 19,20,21,22,23,24,25,26 , chondrocyte-like cells 27,28 , mesenchymal stromal cells (MSCs) 13,29,30,31,32,33,34,35 , olfactory 36 , embryonic 37 , hematopoietic 38 , or induced pluripotent 39,40,41 stem cells have been used for regenerative therapy of degenerate discs in basic and/or clinical studies (Table 1)

In participants with mild Alzheimers disease after 1 year of treatment there was a reported 18% less cognitive decline and 50% reduced brain shrinkage compared to placebo

It works by upregulating growth factor expression, promoting angiogenesis, and modulating the nitric oxide system

[DOI] [PMC free article] [PubMed] [Google Scholar] 23.Zhang X, Zhang CC, Yang H, Soni KG, Wang SP, Mitchell GA, et al