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"Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia"
By gathering the hydrophobic chains together in the center of the micelle, disruption of the hydrogen bonded structure of liquid water is minimized, and the polar head groups extend into the surrounding water where they participate in hydrogen bonding

Certain gut bacteria metabolize this unabsorbed carnitine into a compound called Trimethylamine (TMA)

Circulation 87 , 19601968 (1993)
