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According to the extraction experiment and molecular docking results, alkaloids of FRP, such as palmatine and berberine, were not only the most abundant components in FRP but also had the best anti-AD activity
The proteolytic cleavage of pro-somatostatin in the basic domain (Arg/Lys) or the monobasic domain (Arg) of the C-terminal end gives rise to SS-14 and SS-28, respectively (Figure 3)
Lipoic acid, a compound containing sulfur in the form of two thiol groups, acts as a cofactor for several mitochondrial enzymes by catalyzing alpha-keto acids
