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TRANSLATION OF INHALED EXPOSURE THROUGHOUT DRUG DEVELOPMENT: A CASESTUDY ON HOW TO DERISK FORMULATION DEVELOPMENT AND SECURE CLINICAL EXPOSURE Rebecca Fransson 1, Carolyn Stevensson2 & Ulrika Tehler1 1Advanced Drug Delivery, Pharmaceutical Science, R&D, AstraZeneca, 43183 Gothenburg, Sweden 2Early Product Development & Manufacturing, Pharmaceutical Science, R&D, AstraZeneca, 43183 Gothenburg, Sweden Summary: Biopharmaceutics is a skill area residing within pharmaceutical sciences and relates the physicochemical properties of a drug in a dosage form to the pharmacology, toxicology, or clinical response observed after its administration

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reported that the deubiquitinase ovarian tumor protein 1 can directly interact and stabilize SLC7A11, thereby inhibiting ferroptosis [68]