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2021), which competitively inhibit the proteinprotein interaction between Keap1 and Nrf2 through non-electrophilic non-covalent compounds, developed to address off-target toxicity from electrophilic compounds (Robledinos-Antn et al

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Interestingly, BCNU pretreatment sensitized hepatocytes to TNF-induced cell death (Fig

Gan L, Cookson MR, Petrucelli L, La Spada AR
