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Description
Activation of integrin receptors in PMNs leads to a signaling cascade that results in the phagocytosis of extracellular pathogens, as well as in superoxide burst (Williams and Solomkin, 1999)
Toxins 5 , 11191139 (2013)
J.TalalayP
The nanoparticles release KGF to decrease intrapulmonary ECM in fibrotic lesions, while MMP13 mRNA is delivered in integrinenriched myofibroblasts and injured AT2 cells to reepithelialize the disrupted alveolar epithelium, synergistically improving lung function and reversing pulmonary fibrosis in mice
